Biomotif can now offer "fee-for-service" contract analysis with our HX-IA Instrument and mass spectrometry for drug development and target validation. We perform H/D exchange studies and analysis of alterations in protein structure following protein/protein or protein/ligand complex formation.
- How many binding sites and where on the target does the drug bind? (Conformational Epitope Mapping)
- Conformational changes due to modifications such as new formulation or new buffer etc.
Pre-concentration of potent peptide or protein drug candidates with ElectroCapture technology.
Tag (derivatize) funtional groups (steriods, hormones and more...) and use our Compound Fishing-Epitope Imprinting technology to affinity capture and detect at ultra low levels in complex biological matrixes.
Contact us with your project and ask for a price estimate!
Download information about HT-HDX and HDX analysis below!